Free Indiana: 2016

Thursday, October 27, 2016

Kytril Tablets

Pronunciation: gra-NIS-e-tron
Generic Name: Granisetron
Brand Name: Kytril

Kytril is used for:

Preventing nausea and vomiting caused by cancer chemotherapy and radiation. It may also be used for other conditions as determined by your doctor.

Kytril is a 5-HT₃ receptor antagonist. It works by blocking a chemical called serotonin that can cause vomiting.

Do NOT use Kytril if:

you are allergic to any ingredient in Kytril

you are taking apomorphine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kytril:

Some medical conditions may interact with Kytril. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you are allergic to other 5-HT₃ receptor antagonists (eg, ondansetron)

if you have heart problems (eg, irregular heartbeat, conduction problems), blood electrolyte problems (eg, low calcium, potassium, or magnesium), an abnormal electrocardiogram (ECG), or you are receiving chemotherapy that may cause heart problems

if you have stomach or bowel problems (eg, pain, swelling) or if you have recently had stomach surgery

Some MEDICINES MAY INTERACT with Kytril. Tell your health care provider if you are taking any other medicines, especially any of the following:

Apomorphine because the risk of side effects, such as severely low blood pressure or loss of consciousness, may occur

Medicines that may affect your heartbeat such as antiarrhythmics (eg, flecainide, sotalol), azole antifungals (eg, ketoconazole) or quinolones (eg, ciprofloxacin) because heart rhythm problems may occur. Ask your doctor if you are unsure if any medicines that you take may affect your heartbeat

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kytril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Kytril:

Use Kytril as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Kytril by mouth with or without food.

Use Kytril only on the days that you receive your cancer treatment, unless otherwise directed by your doctor.

If you miss a dose of Kytril, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Kytril.

Important safety information:

Kytril may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Kytril with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Kytril should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Kytril while you are pregnant. It is not known if Kytril is found in breast milk. If you are or will be breast-feeding while you use Kytril, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Kytril:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; anxiety; constipation; diarrhea; dizziness; drowsiness; headache; indigestion; nausea; stomach pain; taste changes; trouble sleeping; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; fast or irregular heartbeat; fever, chills, or sore throat; unusual muscle movement.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Kytril side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include headache.

Proper storage of Kytril:

Store Kytril at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Kytril out of the reach of children and away from pets.

General information:

If you have any questions about Kytril, please talk with your doctor, pharmacist, or other health care provider.

Kytril is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kytril. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More Kytril resources

Kytril Side Effects (in more detail)
Kytril Dosage
Kytril Use in Pregnancy & Breastfeeding
Drug Images
Kytril Drug Interactions
Kytril Support Group
2 Reviews for Kytril - Add your own review/rating

Compare Kytril with other medications

Nausea/Vomiting, Chemotherapy Induced
Nausea/Vomiting, Postoperative
Nausea/Vomiting, Radiation Induced

Konsyl-Orange

Generic Name: psyllium (SIL ee um)

Brand Names: Fiberall, Hydrocil, Konsyl, Konsyl Orange Sugar-free, Konsyl-D, Konsyl-Orange, Laxmar, Laxmar Orange, Laxmar Sugar Free, Metamucil, Metamucil Berry Burst Smooth Texture Sugar Free, Metamucil Orange Coarse Milled Original Texture, Metamucil Orange Smooth Texture, Metamucil Orange Smooth Texture Sugar Free, Metamucil Original Texture Regular, Metamucil Pink Lemonade Smooth Texture Sugar-Free, Metamucil Unflavored Coarse Milled Original Texture, Metamucil Unflavored Smooth Texture Sugar Free, Natural Fiber Therapy, Perdiem Fiber Powder, Reguloid

What is Konsyl-Orange (psyllium)?

Psyllium is a bulk-forming fiber laxative. Psyllium works by absorbing liquid in the intestines and swelling to create a softer, bulky stool that is easier to pass.

Psyllium is used to treat occasional constipation or bowel irregularity. Psyllium may also be used to treat diarrhea and may help lower cholesterol when used together with a diet low in cholesterol and saturated fat.

Psyllium may also be used for purposes not listed in this product guide.

What is the most important information I should know about Konsyl-Orange (psyllium)?

Laxatives may be habit-forming if they are used too often or for too long. This can lead to damage of intestinal nerves or muscle tissues. Do not take psyllium for longer than directed on the label or prescribed by your doctor. You should not take this product if you are allergic to psyllium, or if you have trouble swallowing, a sudden change in bowel habits that lasts longer than 2 weeks, severe nausea, vomiting, or stomach pain, or if you have ever had a skin rash while taking psyllium.

Also talk with your doctor before using psyllium if you have a colostomy or ileostomy, rectal bleeding, or a blockage in your intestines.

Stop using psyllium and call your doctor at once if you have choking or trouble swallowing, severe stomach pain or cramping, nausea or vomiting, constipation that lasts longer than 7 days, rectal bleeding, or itchy skin rash. Do not take psyllium for longer than 7 days in a row unless your doctor has told you to.

What should I discuss with my healthcare provider before taking Konsyl-Orange (psyllium)?

trouble swallowing;

a sudden change in bowel habits that lasts longer than 2 weeks;

severe nausea, vomiting, or stomach pain; or

if you have ever had a skin rash while taking psyllium.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

a colostomy or ileostomy;

rectal bleeding; or

a blockage in your intestines.

Psyllium products may contain sugar, sodium, or artificial sweeteners. This may be of concern to you if you have diabetes, high blood pressure, or phenylketonuria (PKU). Check the product label if you have any of these conditions.

Psyllium is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether psyllium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Konsyl-Orange (psyllium)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take psyllium with a full glass (at least 8 ounces) of water or another liquid. Taking psyllium without enough liquid may cause it to swell in your throat and cause choking. Drinking plenty of fluids each day while you are taking psyllium will also help improve bowel regularity.

The psyllium wafer must be chewed before you swallow it.

Do not swallow psyllium powder dry. It must be mixed with liquid. Place the psyllium powder into an empty glass and add at least 8 ounces of water or other liquid such as fruit juice. Stir this mixture and drink all of it right away.

If the powder and liquid mixture is too thick, add more liquid. After drinking the entire mixture, add a little more liquid to the same glass, swirl gently and drink right away to make sure you get the entire dose of psyllium.

Psyllium may be only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

It may take up to 3 days of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 2 or 3 days of treatment.

Do not take psyllium for longer than 7 days in a row unless your doctor has told you to. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since psyllium is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using psyllium.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and stomach pain. Using a laxative too often or for too long may cause severe medical problems involving your intestines.

What should I avoid while taking Konsyl-Orange (psyllium)?

Avoid taking other oral (by mouth) medications within 2 hours before or after you take psyllium. Bulk-forming laxatives can make it harder for your body to absorb other medications, possibly making them less effective.

Avoid breathing in the dust from psyllium powder when mixing. Inhaling psyllium dust may cause an allergic reaction.

If you take psyllium as part of a cholesterol-lowering treatment plan, avoid eating foods that are high in fat or cholesterol. Your treatment will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Konsyl-Orange (psyllium) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using psyllium and call your doctor at once if you have a serious side effect such as:

choking or trouble swallowing;

severe stomach pain, cramping, nausea or vomiting;

constipation that lasts longer than 7 days;

rectal bleeding; or

itchy skin rash.

Less serious side effects may include:

bloating; or

minor change in your bowel habits.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Konsyl-Orange (psyllium)?

Tell your doctor about all other medications you use, especially:

a blood thinner such as warfarin (Coumadin, Jantoven); or

demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and other drugs may interact with psyllium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Konsyl-Orange resources

Konsyl-Orange Side Effects (in more detail)
Konsyl-Orange Use in Pregnancy & Breastfeeding
Konsyl-Orange Drug Interactions
Konsyl-Orange Support Group
0 Reviews for Konsyl-Orange - Add your own review/rating

Konsyl Powder MedFacts Consumer Leaflet (Wolters Kluwer)

Metamucil MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Konsyl-Orange with other medications

Constipation
Dietary Fiber Supplementation
Irritable Bowel Syndrome

Where can I get more information?

Your pharmacist can provide more information about psyllium.

See also: Konsyl-Orange side effects (in more detail)

Koate DVI

Generic Name: antihemophilic factor (Intravenous route)

an-tee-hee-moe-FIL-ik FAK-tor

Commonly used brand name(s)

In the U.S.

Advate

Helixate FS

Hemofil-M

Hyate:C

Koate DVI

Kogenate FS

Kogenate FS w/BIO-SET

Monarc-M

Monoclate-P

Recombinate

Refacto

Xyntha

Available Dosage Forms:

Powder for Solution

Therapeutic Class: Antihemophilic Agent

Uses For Koate DVI

Antihemophilic factor (AHF) injection is used to treat serious bleeding episodes in patients with a bleeding problem called hemophilia A. The bleeding episode may be related to an injury (trauma) or a surgical procedure. AHF is a protein that is produced naturally in the body. It helps the blood form clots to stop bleeding and prevents bleeding problems from happening as often.

Hemophilia A, also called classical hemophilia, is a condition where the body does not make enough AHF. If you do not have enough AHF and you become injured, your blood will not form clots properly. You might bleed into and damage your muscles and joints. AHF injection is given to increase the levels of AHF in the blood.

There are several different types of AHF. They are made from human blood or artificially by a man-made process (recombinant). AHF made from human blood has been treated and is not likely to contain harmful viruses, such as hepatitis B, hepatitis C, or human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). The man-made AHF products do not contain these viruses.

This medicine is available only with your doctor's prescription.

Before Using Koate DVI

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of antihemophilic factor injection in children.

No information is available on the relationship of age to the effects of Hemofil® M in the pediatric population. Safety and efficacy have not been established.

Geriatric

Although appropriate studies on the relationship of age to the effects of Advate® have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related medical problems, which may require caution and an adjustment in the dose for patients receiving Advate®.

No information is available on the relationship of age to the effects of antihemophilic factor injection in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of antihemophilic factor

This section provides information on the proper use of a number of products that contain antihemophilic factor. It may not be specific to Koate DVI. Please read with care.

A doctor or other trained health professional will give you or your child this medicine in a hospital or clinic setting. This medicine is given through a needle placed in one of your veins.

This medicine may also be given at home to patients who do not need to be in a hospital or clinic. If you or your child are using this medicine at home, your doctor will teach you how to prepare and inject the medicine. Make sure you understand all of the instructions before giving yourself an injection. Your dose may change based on where you are bleeding. Do not use more medicine or use it more often than your doctor tells you to.

Use only the brand of this medicine that your doctor prescribed. Not all brands are prepared in the same way and the dose may be different.

Every package of medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

To prepare the medicine using 2 bottles (vials) or containers:

Take the bottles of powder medicine and liquid (diluent) out of the refrigerator and warm them to room temperature.

Wipe the rubber surface of the bottles with an alcohol swab and allow them to dry.

Follow the specific directions for your brand of medicine when you prepare the injection.

Add the liquid to the powder using the special transfer needle or transfer device that comes with the package.

When injecting the liquid into the dry medicine, aim the stream of liquid against the wall of the container of dry medicine to prevent foaming.

Swirl the bottle gently to dissolve the medicine. Do not shake the bottle. Shaking will create foam in the mixture.

Check the mixture to make sure it is clear. Do not use the medicine if you can see anything solid in the mixture or if the mixture is cloudy.

Use a plastic disposable syringe to remove the mixture from the bottle. Use a special filter needle if your brand of medicine provides one.

Give the injection as directed by your doctor.

If you are using more than one bottle of medicine for your dose, prepare the second bottle the same way. Add the mixture from the second bottle to the same syringe.

To prepare the medicine using a prefilled dual-chamber syringe (Xyntha®):

Take the prefilled dual-chamber syringe out of the refrigerator and warm it to room temperature.

The dual-chamber syringe has the powder medicine in one part and the liquid (diluent) in the second part of the syringe.

Attach the plunger rod to the syringe according to the directions. Keep the syringe pointed up to prevent leaking of the liquid.

Remove the white seal and the grey rubber tip cap. Put the blue vented cap on the syringe. Do not touch the open ends of the syringe and the blue cap.

Slowly push the plunger until the 2 stoppers inside the syringe are together. This will push all of the liquid into the chamber with the powder medicine.

Keep the syringe pointed up and gently swirl the syringe to mix the liquid and powder.

Check the mixture to make sure it is clear. Do not use the medicine if you can see anything solid in the mixture or if the mixture is cloudy.

Keep the syringe pointed up and push the plunger until most of the air is removed.

A special infusion set comes with the package. Remove the blue cap and attach the infusion set to the syringe.

Give the injection as directed by your doctor.

If you are using more than one syringe of medicine for your dose, prepare the second dual-chamber syringe the same way. The mixture from each syringe will be combined together in a separate syringe before your injection. Your doctor will show you how to do this.

Use the mixture within 3 hours after it is prepared. It must not be stored and used later. Do not put the mixture in the refrigerator.

Do not reuse syringes and needles. Put used syringes and needles in a puncture-resistant disposable container, or dispose of them as directed by your doctor.

Talk to your doctor before traveling. You should plan to bring enough medicine for your treatment when traveling.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For injection dosage form (injection):
- For bleeding episodes in patients with hemophilia A:
  - Adults and teenagers—Dose is based on body weight and the type of bleeding episode. The dose must be determined by your doctor.
  - Children—Dose is based on body weight and the type of bleeding episode. The dose must be determined by your child's doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

The AHF products should be stored in the original container in the refrigerator. Do not let the packages freeze. They can also be kept at room temperature for short periods of time, such as 3 to 6 months. Store the medicine as directed by your doctor or by the manufacturer of the brand you are using. Protect the container from heat and direct light.

If you move the medicine from the refrigerator to room temperature, write the date you take it from the refrigerator on the container. The length of time the medicine can remain at room temperature will depend on the brand you use. If you have already stored the medicine at room temperature, do not return it to the refrigerator. If you do not use the medicine within the time recommended by the manufacturer, you must destroy the medicine.

Precautions While Using Koate DVI

It is very important that your doctor check you or your child closely while you are receiving this medicine to make sure it is working properly. Blood tests may be needed.

This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop using this medicine and check with your doctor right away if you or your child have a rash; itching; hoarseness; trouble breathing; trouble swallowing; lightheadedness or dizziness; or any swelling of your hands, face, or mouth after you receive this medicine.

It is recommended that you carry an identification (ID) card or letter stating that you have hemophilia A and the type of medicine you are using. If you have any questions about what kind of identification to carry, check with your doctor.

Check with your doctor right away if you have any symptoms of parvovirus infection: fever, chills, drowsiness, runny nose, and followed by a rash or joint pain.

Check with your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.

This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during manufacture of these medicines. Although the risk is low, talk with your doctor if you have any concerns.

The stopper of the bottle (vial) contains dry natural rubber (a derivative of latex), which may cause allergic reactions in people who are sensitive to latex. Tell your doctor if you have a latex allergy before you start using this medicine.

Koate DVI Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fever

Less common or rare

Changes in facial skin color

chills

fast or irregular breathing

nausea

puffiness or swelling of the eyelids or around the eyes

sensation of burning, warmth, heat, numbness, tightness, or tingling

shortness of breath

skin rash, hives, or itching

tightness in the chest

troubled breathing

unusual tiredness or weakness

wheezing

Incidence not known

Bluish color of the fingernails, lips, skin, palms, or nail beds

blurred vision

chest pain or discomfort

confusion

cough

deep or fast breathing with dizziness

difficult or labored breathing

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse

noisy breathing

numbness of the feet, hands, and around the mouth

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

slow or irregular heartbeat

sweating

swelling of the face, throat, or tongue

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Less common

Burning, stinging, or swelling at the place of injection

diarrhea

dizziness or lightheadedness

dry mouth or bad taste in the mouth

lack or loss of strength

nosebleed

redness of the face

vomiting

Rare

Change in taste

loss of taste

Incidence not known

Abdominal or stomach pain

feeling of warmth

increased sweating

irritability

muscle or bone pain

redness of the eye

redness of the face, neck, arms, and occasionally, upper chest

redness of the skin

trouble seeing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Koate DVI side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Koate DVI resources

Koate DVI Side Effects (in more detail)
Koate DVI Use in Pregnancy & Breastfeeding
Koate DVI Support Group
0 Reviews for Koate DVI - Add your own review/rating

Compare Koate DVI with other medications

Hemophilia A

Kronofed-A

Generic Name: chlorpheniramine and pseudoephedrine (klor fen EER a meen and soo doe e FED rin)

Brand Names: AccuHist Drops, Allerest Maximum Strength, Brexin L.A., Colfed-A, D-Amine-SR, Dayquil Allergy, Deconamine, Dicel, Dicel Chewables, Dura-Tap/PD, Durafed, Duratuss DA, Dynahist-ER Pediatric, Genaphed Plus, Histade, Histex, Kronofed-A, Kronofed-A-Jr, LoHist-D, Mintex, Neutrahist Drops, Re2+30, Rescon-Ed, Suclor, SudaHist, Sudal-12 Chewable, Sudal-12 Tannate, Sudogest Cold & Allergy, SudoGest Sinus & Allergy, Tavist-DA, Triaminic Cold and Allergy, Triaminic Softchew Cold and Allergy, Triaminic Softchews Allergy Runny Nose and Congestion

What is Kronofed-A (chlorpheniramine and pseudoephedrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine and pseudoephedrine is used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.

Chlorpheniramine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Kronofed-A (chlorpheniramine and pseudoephedrine)?

There are many brands and forms of this medication available and not all brands are listed on this leaflet.

Do not use chlorpheniramine and pseudoephedrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. You should not use this medication if you are allergic to chlorpheniramine or pseudoephedrine, or if you have severe high blood pressure or coronary artery disease, narrow-angle glaucoma, a stomach ulcer, or if you are unable to urinate.

Do not use this medication during an asthma attack.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine and pseudoephedrine. Older adults may be more likely to have side effects from this medicine. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

What should I discuss with my healthcare provider before taking Kronofed-A (chlorpheniramine and pseudoephedrine)?

severe or uncontrolled high blood pressure;

severe coronary artery disease;

narrow angle glaucoma;

a stomach ulcer;

if you are unable to urinate; or

if you are having an asthma attack.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:

kidney disease;

liver disease;

diabetes;

glaucoma;

circulation problems;

heart disease or high blood pressure;

overactive thyroid;

a seizure disorder such as epilepsy;

asthma, emphysema or chronic bronchitis; or

urination problems or an enlarged prostate.

FDA pregnancy category C. It is not known whether chlorpheniramine and pseudoephedrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether chlorpheniramine and pseudoephedrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine.

Artificially sweetened liquid cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take Kronofed-A (chlorpheniramine and pseudoephedrine)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

The chewable tablet must be chewed before swallowing.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

This medication can cause unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cold medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.

What should I avoid while taking Kronofed-A (chlorpheniramine and pseudoephedrine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine and pseudoephedrine. Ask a doctor or pharmacist before using any other cold, allergy, or sleep medicine. Chlorpheniramine and pseudoephedrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or decongestant.

Avoid taking this medication if you also take diet pills, caffeine pills, or other stimulants (such as ADHD medications). Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Kronofed-A (chlorpheniramine and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

fast or pounding heartbeats;

confusion, hallucinations, unusual thoughts or behavior;

severe dizziness, anxiety, restless feeling, nervousness;

urinating less than usual or not at all;

easy bruising or bleeding, unusual weakness; or

seizure (black-out or convulsions).

Less serious side effects may include:

blurred vision;

dry nose or mouth;

nausea, stomach pain, constipation, loss of appetite;

dizziness, drowsiness;

problems with memory or concentration;

ringing in your ears; or

feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

What other drugs will affect Kronofed-A (chlorpheniramine and pseudoephedrine)?

Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by chlorpheniramine.

Tell your doctor about all other medications you use, especially:

mecamylamine (Inversine);

methyldopa (Aldomet);

reserpine;

a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton); or

an antidepressant such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), nortriptyline (Pamelor), and others.

This list is not complete and other drugs may interact with chlorpheniramine and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Kronofed-A resources

Kronofed-A Use in Pregnancy & Breastfeeding
Kronofed-A Drug Interactions
Kronofed-A Support Group
0 Reviews for Kronofed-A - Add your own review/rating

AccuHist Drops Prescribing Information (FDA)

Biohist LA Sustained-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Deconamine MedFacts Consumer Leaflet (Wolters Kluwer)

Deconamine SR Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Duotan Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

QDALL 24-Hour Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Kronofed-A with other medications

Hay Fever
Sinusitis

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine and pseudoephedrine.

Ku-Zyme HP

Generic Name: pancrelipase (oral) (pan kre LYE pace)

Brand Names: Cotazym, Creon, Dygase, Ku-Zyme, Ku-Zyme HP, Kutrase, Lapase, Palcaps 10, Pancrease MT 10, Pancrease MT 16, Pancrease MT 20, Pancrease MT 4, Pancrecarb MS-16, Pancrecarb MS-4, Pancrecarb MS-8, Panocaps, Panocaps MT 16, Ultrase, Ultrase MT 12, Ultrase MT 18, Ultrase MT 20, Viokase, Viokase 16, Zenpep

What is pancrelipase?

Pancrelipase is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars.

Pancrelipase is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts.

Pancrelipase may also be used following surgical removal of the pancreas.

Pancrelipase may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about pancrelipase?

You should not take pancrelipase if you are allergic to pork proteins.

Before taking pancrelipase, tell your doctor if you have gout, kidney disease, a history of intestinal blockage, a sudden onset of pancreatitis, or worsening of chronic pancreatic disease.

Use pancrelipase regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not hold the tablets or capsule contents in your mouth. The medication may irritate the inside of your mouth.

Do not inhale the powder from a pancrelipase capsule, or allow it to touch your skin. It may cause irritation, especially to your nose and lungs.

If you miss a dose of this medicine, skip the missed dose and wait until your next scheduled dose to take the medicine. Do not take extra medicine to make up the missed dose.

What should I discuss with my healthcare provider before taking pancrelipase?

You should not take pancrelipase if you are allergic to pork proteins.

If you have any of these other conditions, you may need a pancrelipase dose adjustment or special tests:

kidney disease;

gout;

a history of blockage in your intestines;

a sudden onset of pancreatitis; or

worsening of chronic pancreatic disease.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether pancrelipase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take pancrelipase?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Pancrelipase should be taken with a meal or snack. Take the medicine with a full glass of water or juice.

Do not hold the tablets or capsule contents in your mouth. The medication may irritate the inside of your mouth.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

You may open the pancrelipase capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

Do not inhale the powder from a pancrelipase capsule, or allow it to touch your skin. It may cause irritation, especially to your nose and lungs.

Use pancrelipase regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store in the original container at room temperature (below 78 degrees F) for up to 12 weeks. Protect from moisture or high heat. Keep the bottle tightly closed when not in use. If the medication is exposed to temperatures between 78 and 104 degrees F, throw it away after 30 days. Do not use any pancrelipase that has been exposed to temperatures above 104 degrees F.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include diarrhea or stomach upset.

What should I avoid while taking pancrelipase?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Pancrelipase side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have severe or unusual stomach pain. This could be a symptom of a rare but serious bowel disorder.

Less serious side effects may include:

nausea or vomiting;

mild stomach pain or upset;

diarrhea or constipation;

bloating or gas.

greasy stools;

rectal irritation;

headache, dizziness;

cough; or

weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect pancrelipase?

There may be other drugs that can interact with pancrelipase. Tell your doctor about all medications you use. This includes prescription, over the counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Ku-Zyme HP resources

Ku-Zyme HP Side Effects (in more detail)
Ku-Zyme HP Use in Pregnancy & Breastfeeding
Drug Images
Ku-Zyme HP Drug Interactions
Ku-Zyme HP Support Group
0 Reviews for Ku-Zyme HP - Add your own review/rating

Pancrelipase Professional Patient Advice (Wolters Kluwer)

Pancrelipase Prescribing Information (FDA)

Pancrelipase Monograph (AHFS DI)

Pancrelipase MedFacts Consumer Leaflet (Wolters Kluwer)

Creon Prescribing Information (FDA)

Creon Advanced Consumer (Micromedex) - Includes Dosage Information

Creon MedFacts Consumer Leaflet (Wolters Kluwer)

Creon Consumer Overview

Creon 10 Delayed-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Dygase MedFacts Consumer Leaflet (Wolters Kluwer)

Pancreaze Consumer Overview

Pancreaze Prescribing Information (FDA)

Zenpep Prescribing Information (FDA)

Zenpep Consumer Overview

Compare Ku-Zyme HP with other medications

Chronic Pancreatitis
Cystic Fibrosis
Pancreatic Exocrine Dysfunction

Where can I get more information?

Your pharmacist can provide more information about pancrelipase.

See also: Ku-Zyme HP side effects (in more detail)

Kronofed-A-Jr

What is Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine and pseudoephedrine is used to treat symptoms of the common cold or seasonal allergies, including sneezing, runny or stuffy nose, and itchy, watery eyes.

Chlorpheniramine and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

There are many brands and forms of this medication available and not all brands are listed on this leaflet.

Do not use this medication during an asthma attack.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

What should I discuss with my healthcare provider before taking Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

severe or uncontrolled high blood pressure;

severe coronary artery disease;

narrow angle glaucoma;

a stomach ulcer;

if you are unable to urinate; or

if you are having an asthma attack.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:

kidney disease;

liver disease;

diabetes;

glaucoma;

circulation problems;

heart disease or high blood pressure;

overactive thyroid;

a seizure disorder such as epilepsy;

asthma, emphysema or chronic bronchitis; or

urination problems or an enlarged prostate.

Artificially sweetened liquid cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

The chewable tablet must be chewed before swallowing.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

This medication can cause unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

If you need surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include some of the serious side effects listed in this medication guide.

What should I avoid while taking Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine and pseudoephedrine. Ask a doctor or pharmacist before using any other cold, allergy, or sleep medicine. Chlorpheniramine and pseudoephedrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or decongestant.

Kronofed-A-Jr (chlorpheniramine and pseudoephedrine) side effects

fast or pounding heartbeats;

confusion, hallucinations, unusual thoughts or behavior;

severe dizziness, anxiety, restless feeling, nervousness;

urinating less than usual or not at all;

easy bruising or bleeding, unusual weakness; or

seizure (black-out or convulsions).

Less serious side effects may include:

blurred vision;

dry nose or mouth;

nausea, stomach pain, constipation, loss of appetite;

dizziness, drowsiness;

problems with memory or concentration;

ringing in your ears; or

feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

What other drugs will affect Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

Tell your doctor about all other medications you use, especially:

mecamylamine (Inversine);

methyldopa (Aldomet);

reserpine;

a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton); or

an antidepressant such as amitriptyline (Elavil, Vanatrip), doxepin (Sinequan), nortriptyline (Pamelor), and others.

More Kronofed-A-Jr resources

Kronofed-A-Jr Use in Pregnancy & Breastfeeding
Kronofed-A-Jr Drug Interactions
Kronofed-A-Jr Support Group
0 Reviews for Kronofed-A-Jr - Add your own review/rating

AccuHist Drops Prescribing Information (FDA)

Biohist LA Sustained-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Deconamine MedFacts Consumer Leaflet (Wolters Kluwer)

Deconamine SR Controlled-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Duotan Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

QDALL 24-Hour Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Kronofed-A-Jr with other medications

Hay Fever
Sinusitis

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine and pseudoephedrine.

Kombiglyze XR

Generic Name: metformin and saxagliptin (met FOR min and SAX a GLIP tin)

Brand Names: Kombiglyze XR

What is metformin and saxagliptin?

Metformin and saxagliptin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Saxagliptin works by regulating the levels of insulin your body produces after eating.

The combination of metformin and saxagliptin is used to treat type 2 diabetes. This medication is not for treating type 1 diabetes.

Metformin and saxagliptin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about metformin and saxagliptin?

You should not use this medication if you are allergic to metformin (Actoplus Met, Avandamet, Fortamet, Glucophage, Riomet) or saxagliptin (Onglyza), if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin and saxagliptin.

Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or irregular heart rate, dizziness, or feeling very weak or tired.

What should I discuss with my healthcare provider before taking metformin and saxagliptin?

Some people develop a life-threatening condition called lactic acidosis while taking metformin. You may be more likely to develop lactic acidosis if you have liver or kidney disease, heart attack or congestive heart failure, a severe infection, if you are dehydrated, or if you drink large amounts of alcohol. Do not use this medication if you are allergic to metformin (Actoplus Met, Avandamet, Fortamet, Glucophage, Riomet) or saxagliptin (Onglyza), if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin and saxagliptin. Be sure your caregivers know ahead of time that you are using this medication.

To make sure you can safely take metformin and saxagliptin, tell your doctor if you have any of these other conditions:

liver disease;

heart disease; or

if you are over 80 years old;

Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with metformin and saxagliptin. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether metformin and saxagliptin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take metformin and saxagliptin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

Take metformin and saxagliptin with a meal. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.

Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.

Ask your doctor how to adjust your metformin and saxagliptin dose if needed. Do not change your medication dose or schedule without your doctor's advice.

Metformin and saxagliptin is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, and eye care. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

See also: Kombiglyze XR dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions). An overdose of metformin may cause lactic acidosis. Get emergency medical help if you have: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.

What should I avoid while taking metformin and saxagliptin?

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

Metformin and saxagliptin side effects

This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or irregular heart rate, dizziness, or feeling very weak or tired. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have a serious side effect such as:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;

pain or burning when you urinate; or

swelling or rapid weight gain.

Less serious side effects may include:

diarrhea, mild nausea;

headache; or

cold symptoms such as runny or stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect metformin and saxagliptin?

Tell your doctor about all other medicines you use, especially:

another oral diabetes medication such as glipizide (Glucotrol, Metaglip), glimepiride (Amaryl, Avandaryl, Duetact), glyburide (DiaBeta, Micronase, Glucovance), and others;

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), telithromycin (Ketek), trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra), or vancomycin (Vancocin, Lyphocin);

antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);

heart or blood pressure medication such as amiloride (Midamor), digoxin (Lanoxin), diltiazem (Cartia, Cardizem), furosemide (Lasix), nifedipine (Nifedical), procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), triamterene (Dyrenium), and others; or

HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra).

You may be more likely to have hyperglycemia (high blood sugar) if you take metformin and saxagliptin with other drugs that can raise blood sugar, such as:

diuretics (water pills);

steroids (prednisone and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

phenothiazines (Compazine and others);

thyroid medicine (Synthroid and others);

birth control pills and other hormones;

seizure medicines (Dilantin and others); or

diet pills or medicines to treat asthma, colds or allergies.

You may be more likely to have hypoglycemia (low blood sugar) if you take metformin and saxagliptin with other drugs that can lower blood sugar, such as:

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin and others);

heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are not complete and there are many other medicines that can increase or decrease the effects of metformin and saxagliptin on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Kombiglyze XR resources

Kombiglyze XR Side Effects (in more detail)
Kombiglyze XR Dosage
Kombiglyze XR Use in Pregnancy & Breastfeeding
Kombiglyze XR Drug Interactions
1 Review for Kombiglyze XR - Add your own review/rating

Kombiglyze XR Prescribing Information (FDA)

Kombiglyze XR Advanced Consumer (Micromedex) - Includes Dosage Information

Kombiglyze XR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Kombiglyze XR Consumer Overview

Compare Kombiglyze XR with other medications

Diabetes, Type 2

Where can I get more information?

Your pharmacist can provide more information about metformin and saxagliptin.

See also: Kombiglyze XR side effects (in more detail)

Konyne 80

Generic Name: factor IX complex (FAK tor NINE KOM plex)

Brand Names: Bebulin VH, Konyne 80, Profilnine SD, Proplex T

What is Konyne 80 (factor IX complex)?

Factor IX (nine) is a naturally occurring protein in the blood that helps blood to clot. A lack of clotting factors can cause uncontrolled bleeding, as the blood is unable to clot properly.

Factor IX complex is a combination of four different clotting factors and other proteins. This medication works by temporarily raising levels of these clotting factors in the blood to aid in clotting.

Factor IX complex is used to treat or prevent bleeding episodes in people with hemophilia B. It is also used to control bleeding related to surgery or dentistry in people with hemophilia B.

Factor IX may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Konyne 80 (factor IX complex)?

Before using factor IX complex, your specific blood clotting disorder must be diagnosed as factor IX or factor VIII (eight) deficiency.

Your doctor may want you to receive a hepatitis vaccination before you start using factor IX complex.

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label. Always check the strength of the medicine on the label to be sure you are using the correct potency.

Carry an ID card or wear a medical alert bracelet stating that you have hemophilia in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder.

Factor IX complex is made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

What should I discuss with my healthcare provider before using Konyne 80 (factor IX complex)?

Before using factor IX complex, your specific blood clotting disorder must be diagnosed as factor IX or factor VIII (eight) deficiency.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether factor IX complex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Your doctor may want you to receive a hepatitis vaccination before you start using factor IX complex.

How should I use Konyne 80 (factor IX complex)?

Factor IX complex is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Always wash your hands before preparing and giving your injection.

Factor IX complex must be mixed with a liquid (diluent) before injecting it. If you store your medicine in the refrigerator, take a medicine and diluent vial out of the refrigerator and allow each to warm to room temperature before mixing them. Do not heat the medicine or diluent.

After mixing, gently swirl the mixture and allow the medicine to completely dissolve.

After mixing the medicine and diluent, the mixture should be kept at room temperature and must be used within 3 hours. Do not put mixed medicine into the refrigerator.

Draw your dose into a syringe only when you are ready to give yourself an injection. Each vial is for one use only. After measuring your dose, throw the vial away, even if there is medicine left in it.

Do not use this medication if it has changed colors or has any particles in it. Call your doctor for a new prescription.

Check your pulse before and during your injection. If your pulse rate changes, slow or stop the injection until your pulse rate returns to normal.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Throw away any leftover medicine and diluent if the expiration date has passed.

What happens if I miss a dose?

Factor IX is sometimes used only as needed, so you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Call your doctor if you think you have used too much of this medicine. An overdose of factor IX complex is not expected to produce life-threatening symptoms.

What should I avoid while using Konyne 80 (factor IX complex)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using factor IX complex.

Konyne 80 (factor IX complex) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; nausea, vomiting; feeling light-headed, fainting; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

cough, chest pain;

weak or shallow breathing;

feeling short of breath;

headache, feeling like you might pass out;

fever, chills, drowsiness, and runny nose followed by skin rash and joint pain 2 weeks later;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

easy bruising, increased bleeding episodes; or

bleeding from a wound or where the medicine was injected.

Less serious side effects may include:

mild nausea or stomach pain; or

mild tingly or jittery feeling.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Konyne 80 (factor IX complex)?

There may be other drugs that can affect factor IX complex. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Konyne 80 resources

Konyne 80 Side Effects (in more detail)
Konyne 80 Use in Pregnancy & Breastfeeding
Konyne 80 Drug Interactions
Konyne 80 Support Group
0 Reviews for Konyne 80 - Add your own review/rating

Bebulin VH Prescribing Information (FDA)

Bebulin VH Advanced Consumer (Micromedex) - Includes Dosage Information

Bebulin VH MedFacts Consumer Leaflet (Wolters Kluwer)

Profilnine SD Prescribing Information (FDA)

Compare Konyne 80 with other medications

Factor IX Deficiency
Factor VII Deficiency
Hemophilia A with Inhibitors
Hemophilia B

Where can I get more information?

Your doctor or pharmacist can provide more information about factor IX.

See also: Konyne 80 side effects (in more detail)

Kwellada Lotion 1% Topical

Generic Name: lindane (Topical route)

LIN-dane

Topical route(Lotion;Shampoo)

Lindane should only be used in patients who cannot tolerate or have failed first-line treatment with safer medications for the treatment of scabies. Seizures and deaths have been reported following lindane use. Risk of serious neurotoxicity when used in infants, children, the elderly, individuals with other skin conditions (eg, atopic dermatitis, psoriasis), and in those who weigh less than 110 lbs (50 kg). Lindane is contraindicated in premature infants and individuals with known uncontrolled seizure disorders. Instruct patients on the proper use of lindane .

Commonly used brand name(s)

In the U.S.

Kwell

Thionex

In Canada

Kwellada Lotion 1%

Lindane

Pms-Lindane

Available Dosage Forms:

Cream

Shampoo

Lotion

Therapeutic Class: Scabicide

Uses For Kwellada Lotion 1%

Lindane , formerly known as gamma benzene hexachloride, is an insecticide and is used to treat scabies and lice infestations.

Lindane cream and lotion are usually used to treat only scabies infestation. Lindane shampoo is used to treat only lice infestations.

Lindane is available only with your doctor's prescription.

Before Using Kwellada Lotion 1%

Allergies

Pediatric

Infants and children or people who weigh less than 110 pounds (50 kilograms) are especially sensitive to the effects of lindane. This may increase the chance of serious side effects during treatment. Be sure you have discussed the risks and benefits of using this medicine with your doctor. In addition, use of lindane is not to be used in premature infants.

Geriatric

Elderly people or people who weigh less than 110 pounds (50 kilograms) are especially sensitive to the effects of lindane. This may increase the chance of serious side effects during treatment. Be sure you have discussed the risks and benefits of this medicine with your doctor.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of lindane

This section provides information on the proper use of a number of products that contain lindane. It may not be specific to Kwellada Lotion 1%. Please read with care.

Lindane is poisonous. Keep it away from the mouth because it is harmful and may be fatal if swallowed.

Use lindane only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may increase the chance of absorption through the skin and the chance of lindane poisoning.

Keep lindane away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water at once and contact your doctor.

Do not use lindane on open wounds, such as cuts or sores on the skin or scalp. To do so may increase the chance of lindane poisoning.

When applying lindane to another person, you should wear plastic disposable or rubber gloves made of latex or vinyl, especially if you are pregnant or are breast-feeding. Do not use natural latex gloves because lindane can go through those gloves and be absorbed by your skin. Wash hands very well after applying the lotion. This will prevent lindane from being absorbed through your skin. If you have any questions about this, check with your healthcare professional.

Put lindane lotion under fingernails, and trim fingernails short. Use a toothbrush to get the lindane lotion under fingernails, and throw out the toothbrush when finished.

Do not cover the area completely. Use a light clothing.

Lindane comes with patient directions. Be sure that you read them very carefully before using lindane. If you have any questions check with your healthcare professional.

Your sexual partner or partners, especially, and all members of your household may need to be treated also, since the infestation may spread to persons in close contact. If these persons have not been checked for an infestation or if you have any questions about this, check with your healthcare professional

To use the cream or lotion form of lindane for scabies :

If your skin has any cream, lotion, ointment, or oil on it, wash, rinse, and dry your skin well before applying lindane.

If you take a warm bath or shower before using lindane, dry the skin well before applying it.

Apply enough lindane to your dry skin to cover the entire skin surface from the neck down, including the soles of your feet, and rub in well.

Leave lindane on for 8 to 12 hours, then remove by washing thoroughly.

To use the shampoo form of lindane for lice:

If your hair has any cream, lotion, ointment, or oil-based product on it, shampoo, rinse, and dry your hair and scalp well before applying lindane.

If you apply this shampoo in the shower or in the bathtub, make sure the shampoo is not allowed to run down on other parts of your body. Also, do not apply this shampoo in a bathtub where the shampoo may run into the bath water in which you are sitting. To do so may increase the chance of absorption through the skin. When you rinse out the shampoo, be sure to thoroughly rinse your entire body also to remove any shampoo that may have gotten on it.

Apply enough shampoo to your dry hair (1 ounce or less for short hair, 1½ ounces for medium length hair, and 2 ounces or less for long hair) to thoroughly wet the hair and skin or scalp of the affected and surrounding hairy areas.

Thoroughly rub the shampoo into the hair and skin or scalp and allow to remain in place for 4 minutes. Then, use just enough water to work up a good lather.

Rinse thoroughly and dry with a clean towel.

When the hair is dry, comb with a fine-toothed comb to remove any remaining nits (eggs) or nit shells.

Do not use as a regular shampoo.

Dosing

For cream and lotion dosage forms:
- For scabies:
  - Adults and children—Apply to the affected area(s) of the skin one time.
  - Premature infants—Use is not recommended.

For shampoo dosage form:
- For lice:
  - Adults and children—Apply to the scalp or the affected area(s) of the skin one time.
  - Premature infants—Use is not recommended.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Kwellada Lotion 1%

To help prevent reinfestation or spreading of the infestation to other persons:

For scabies—All recently worn underwear and pajamas and used sheets, pillowcases, and towels should be washed in very hot water or dry-cleaned.

For lice—All recently worn clothing and used bed linens and towels should be washed in very hot water or dry-cleaned.

Kwellada Lotion 1% Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Convulsions (seizures)

dizziness, clumsiness, or unsteadiness

fast heartbeat

muscle cramps

nervousness, restlessness, or irritability

vomiting

skin irritation not present before use of lindane

skin rash

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Serious side effects have resulted in patients using lindane. Sometime it has occurred even when used according to the labeled directions. Serious side effects have been reported following lindane use with repeat or prolonged use, but also in rare cases following a single application. You should discuss these possible effects with your doctor.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Kwellada% Topical side effects (in more detail)

More Kwellada Lotion 1% Topical resources

Kwellada Lotion 1% Topical Side Effects (in more detail)
Kwellada Lotion 1% Topical Use in Pregnancy & Breastfeeding
Kwellada Lotion 1% Topical Drug Interactions
Kwellada Lotion 1% Topical Support Group
0 Reviews for Kwellada% Topical - Add your own review/rating

Compare Kwellada Lotion 1% Topical with other medications

Head Lice
Lice
Scabies

Thursday, October 27, 2016

Kytril is used for:

Do NOT use Kytril if:

Before using Kytril:

How to use Kytril:

Important safety information:

Possible side effects of Kytril:

If OVERDOSE is suspected:

General information:

More Kytril resources

Compare Kytril with other medications

What is Konsyl-Orange (psyllium)?

What is the most important information I should know about Konsyl-Orange (psyllium)?

What should I discuss with my healthcare provider before taking Konsyl-Orange (psyllium)?

How should I take Konsyl-Orange (psyllium)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Konsyl-Orange (psyllium)?

Konsyl-Orange (psyllium) side effects

What other drugs will affect Konsyl-Orange (psyllium)?

More Konsyl-Orange resources

Compare Konsyl-Orange with other medications

Where can I get more information?

Commonly used brand name(s)

Uses For Koate DVI

Before Using Koate DVI

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of antihemophilic factor

Dosing

Missed Dose

Storage

Precautions While Using Koate DVI

Koate DVI Side Effects

More Koate DVI resources

Compare Koate DVI with other medications

What is Kronofed-A (chlorpheniramine and pseudoephedrine)?

What is the most important information I should know about Kronofed-A (chlorpheniramine and pseudoephedrine)?

What should I discuss with my healthcare provider before taking Kronofed-A (chlorpheniramine and pseudoephedrine)?

How should I take Kronofed-A (chlorpheniramine and pseudoephedrine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Kronofed-A (chlorpheniramine and pseudoephedrine)?

Kronofed-A (chlorpheniramine and pseudoephedrine) side effects

What other drugs will affect Kronofed-A (chlorpheniramine and pseudoephedrine)?

More Kronofed-A resources

Compare Kronofed-A with other medications

Where can I get more information?

What is pancrelipase?

What is the most important information I should know about pancrelipase?

What should I discuss with my healthcare provider before taking pancrelipase?

How should I take pancrelipase?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking pancrelipase?

Pancrelipase side effects

What other drugs will affect pancrelipase?

More Ku-Zyme HP resources

Compare Ku-Zyme HP with other medications

Where can I get more information?

What is Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

What is the most important information I should know about Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

What should I discuss with my healthcare provider before taking Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

How should I take Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

Kronofed-A-Jr (chlorpheniramine and pseudoephedrine) side effects

What other drugs will affect Kronofed-A-Jr (chlorpheniramine and pseudoephedrine)?

More Kronofed-A-Jr resources

Compare Kronofed-A-Jr with other medications

Where can I get more information?

What is metformin and saxagliptin?

What is the most important information I should know about metformin and saxagliptin?