Kytril Solution

Pronunciation: gra-NIS-e-tron
Generic Name: Granisetron
Brand Name: Kytril

Kytril Solution is used for:

Preventing nausea and vomiting caused by cancer chemotherapy and radiation. It may also be used for other conditions as determined by your doctor.

Kytril Solution is a 5-HT₃ receptor antagonist. It works by blocking a chemical called serotonin that can cause vomiting.

Do NOT use Kytril Solution if:

• you are allergic to any ingredient in Kytril Solution


• you are taking apomorphine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kytril Solution:

Some medical conditions may interact with Kytril Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you are allergic to other 5-HT₃ receptor antagonists (eg, ondansetron)


• if you have heart problems (eg, irregular heartbeat, conduction problems), blood electrolyte problems (eg, low calcium, potassium or magnesium), an abnormal electrocardiogram (ECG), or you are receiving chemotherapy that may cause heart problems


• if you have stomach or bowel problems (eg, pain, swelling) or if you have recently had stomach surgery

Some MEDICINES MAY INTERACT with Kytril Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Apomorphine because the risk of side effects, such as severely low blood pressure or loss of consciousness, may occur


• Medicines that may affect your heartbeat, such as antiarrhythmics (eg, flecainide, sotalol), azole antifungals (eg, ketoconazole), or quinolones (eg, ciprofloxacin), because heart rhythm problems may occur. Ask your doctor if you are unsure if any medicines that you take may affect your heartbeat

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kytril Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Kytril Solution:

Use Kytril Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Kytril Solution by mouth with or without food.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• Use Kytril Solution only on the days that you receive your cancer treatment, unless otherwise directed by your doctor.


• If you miss a dose of Kytril Solution, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Kytril Solution.

Important safety information:

• Kytril Solution may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Kytril Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Use Kytril Solution with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Kytril Solution while you are pregnant. It is not known if Kytril Solution is found in breast milk. If you are or will be breast-feeding while you use Kytril Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Kytril Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; anxiety; constipation; diarrhea; dizziness; drowsiness; headache; indigestion; nausea; stomach pain; taste changes; trouble sleeping; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; fast or irregular heartbeat; fever, chills, or sore throat; unusual muscle movement.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Kytril side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include headache.

Proper storage of Kytril Solution:

Store Kytril Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Kytril Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Kytril Solution, please talk with your doctor, pharmacist, or other health care provider.


• Kytril Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kytril Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Kytril resources

• Kytril Side Effects (in more detail)
• Kytril Use in Pregnancy & Breastfeeding
• Drug Images
• Kytril Drug Interactions
• Kytril Support Group
• 2 Reviews for Kytril - Add your own review/rating

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